Structure
T cells
White blood cells that recognize infected cells by the fragments of foreign proteins they display alongside MHC molecules.
Cancer immunotherapy
Treatments that help the immune system attack cancer, such as checkpoint blockade and engineered CAR T cells.Source: Leach et al., 1996Source: June & Sadelain, 2018Source: Maude et al., 2018
Also called CAR T, checkpoint blockade.
Technology or method
How Cancer immunotherapy connects
Cancer immunotherapy uses
Cancer immunotherapy is related to
Technology or method
Monoclonal antibodies
Identical antibodies made by cultures descended from a single fused cell, used in research, diagnostics and medicine.
Studied in
Your progress
Sources & further reading
The explanations on this page are our own summaries of these sources. Follow a link to read the original; if anything here disagrees with it, the original wins. How we choose and check sources.
Enhancement of antitumor immunity by CTLA-4 blockade (opens the original in a new tab)
Leach DR, Krummel MF, Allison JP (1996). Science 271:1734-1736.
Peer-reviewedPrimary researchChimeric antigen receptor therapy (opens the original in a new tab)
June CH, Sadelain M (2018). New England Journal of Medicine 379:64-73.
Peer-reviewedReviewTisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia (opens the original in a new tab)
Maude SL, Laetsch TW, Buechner J, et al. (2018). New England Journal of Medicine 378:439-448.
Peer-reviewedClinical trial