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Helicase

Antimicrobial resistance

Microbes evolving to survive drugs meant to kill them. Bacterial resistance was associated with an estimated 4.95 million deaths in 2019.Source: WHOSource: GRAM Collaborators, 2022Source: CDC, 2025

Also called AMR, antibiotic resistance.

Process

How Antimicrobial resistance connects

Antimicrobial resistance is selected for by

  • Technology or method

    Antibiotics

    Drugs that kill bacteria or stop their growth. Penicillin traces back to Fleming's 1929 report of a mold that stopped bacteria growing.

Antimicrobial resistance is an example of

  • Process

    Natural selection

    Individuals better suited to their surroundings leave more offspring, so their inherited traits become more common. Darwin's finches and peppered moths are well-studied examples.

Antimicrobial resistance is related to

  • Technology or method

    Phage therapy

    Treating bacterial infections with viruses that infect bacteria, an approach being studied again as drug resistance grows.

    Emerging researchOpen in Microbe Lab

Studied in

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Sources & further reading

The explanations on this page are our own summaries of these sources. Follow a link to read the original; if anything here disagrees with it, the original wins. How we choose and check sources.

  1. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis (opens the original in a new tab)

    Antimicrobial Resistance Collaborators (2022). The Lancet 399:629-655.

    Modelled estimate: 1.27 million deaths directly attributable to bacterial AMR in 2019.

    Peer-reviewedSystematic analysis