Level of life
Protein
A chain of amino acids folded into a working shape. Proteins act as enzymes, structures, signals and transporters.
Hemoglobin
The oxygen-carrying protein of red blood cells. Its beta chain is encoded by the HBB gene.Source: MedlinePlusSource: UniProt Consortium
Molecule
How Hemoglobin connects
Hemoglobin is an example of
Hemoglobin is related to
Health condition
Sickle cell disease
An inherited blood disorder caused by a variant in the HBB gene that changes one amino acid in hemoglobin.
Structure
Lungs and breathing
The lungs take in oxygen and remove carbon dioxide from the blood.
Studied in
Your progress
Sources & further reading
The explanations on this page are our own summaries of these sources. Follow a link to read the original; if anything here disagrees with it, the original wins. How we choose and check sources.
HBB gene (opens the original in a new tab)
MedlinePlus Genetics. MedlinePlus Genetics. U.S. National Library of Medicine, NIH.
ReferenceGovernment sourceEducationalUniProtKB P68871: Hemoglobin subunit beta (Homo sapiens) (opens the original in a new tab)
UniProt Consortium. UniProt Knowledgebase. UniProt Consortium (EMBL-EBI, SIB, PIR).
Curated entry noting that beta-globin's initiator methionine is removed (mature chain is residues 2 to 147).
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