Idea or model
Protein structure
Atomic models of proteins, first solved by X-ray crystallography, are shared openly through the Protein Data Bank.
Protein structure prediction
Predicting a protein's three-dimensional shape from its sequence. AlphaFold made accurate predictions possible for many proteins.Source: Jumper et al., 2021Source: Varadi et al., 2022
Also called AlphaFold.
Technology or method
How Protein structure prediction connects
Protein structure prediction describes
Protein structure prediction is an example of
Technology or method
Bioinformatics
Using computers to store, search and analyze biological data such as DNA and protein sequences.
Studied in
Your progress
Sources & further reading
The explanations on this page are our own summaries of these sources. Follow a link to read the original; if anything here disagrees with it, the original wins. How we choose and check sources.
Highly accurate protein structure prediction with AlphaFold (opens the original in a new tab)
Jumper J, Evans R, Pritzel A, et al. (2021). Nature 596:583-589.
Peer-reviewedPrimary researchAlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models (opens the original in a new tab)
Varadi M, Anyango S, Deshpande M, et al. (2022). Nucleic Acids Research 50:D439-D444.
Peer-reviewedPrimary research