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Helicase

Three domains of life

Comparing ribosomal RNA divides life into three domains: Bacteria, Archaea and Eukarya.Source: Woese et al., 1990Source: Woese & Fox, 1977

Idea or model

How Three domains of life connects

Three domains of life describes

  • Organism or group

    Bacteria

    Small single-celled organisms without a nucleus, found almost everywhere on Earth. Most bacteria in the human body are harmless, and some are helpful.

  • Organism or group

    Archaea

    Single-celled organisms without a nucleus that form a separate domain of life from bacteria.

Three domains of life is described by

  • Idea or model

    Common ancestry

    All known cellular life is thought to descend from a last universal common ancestor. Researchers infer its features from genes shared across life, and the details are still debated.

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Sources & further reading

The explanations on this page are our own summaries of these sources. Follow a link to read the original; if anything here disagrees with it, the original wins. How we choose and check sources.

  1. Phylogenetic structure of the prokaryotic domain: the primary kingdoms (opens the original in a new tab)

    Woese CR, Fox GE (1977). Proceedings of the National Academy of Sciences 74:5088-5090.

    Ribosomal RNA comparisons revealed the archaea as a separate lineage.

    Peer-reviewedPrimary research