Technology or method
PCR
The polymerase chain reaction copies a chosen stretch of DNA millions to billions of times.
Microbes that thrive in heat, such as Thermus aquaticus from hot springs, the source of a heat-stable enzyme used in PCR.Source: Brock & Freeze, 1969Source: Chien et al., 1976Source: Saiki et al., 1988
Also called Thermus aquaticus, Taq.
Technology or method
The polymerase chain reaction copies a chosen stretch of DNA millions to billions of times.
The explanations on this page are our own summaries of these sources. Follow a link to read the original; if anything here disagrees with it, the original wins. How we choose and check sources.
Brock TD, Freeze H (1969). Journal of Bacteriology 98:289-297.
Isolation of the hot-spring bacterium later used as the source of Taq polymerase.
Chien A, Edgar DB, Trela JM (1976). Journal of Bacteriology 127:1550-1557.
Saiki RK, Gelfand DH, Stoffel S, et al. (1988). Science 239:487-491.
PCR with heat-stable Taq polymerase.