Process
Adaptive immunity
Slower, highly specific defenses carried out by B and T cells, which remember infections they have met before.
T cells
White blood cells that recognize infected cells by the fragments of foreign proteins they display alongside MHC molecules.Source: Zinkernagel & Doherty, 1974Source: Janeway CA Jr et al., 2001
Step 5 of 7ReadingStructure
How T cells connects
T cells is used by
Technology or method
Cancer immunotherapy
Treatments that help the immune system attack cancer, such as checkpoint blockade and engineered CAR T cells.
T cells is related to
Structure
Dendritic cells
A cell type identified in 1973 that captures antigens and presents them to T cells, linking innate and adaptive immunity.
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Your progress
Sources & further reading
The explanations on this page are our own summaries of these sources. Follow a link to read the original; if anything here disagrees with it, the original wins. How we choose and check sources.
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system (opens the original in a new tab)
Zinkernagel RM, Doherty PC (1974). Nature 248:701-702.
T cells recognize antigen only together with self MHC molecules.
Historical paperPrimary researchImmunobiology: The Immune System in Health and Disease (5th edition) (opens the original in a new tab)
Janeway CA Jr, Travers P, Walport M, et al. (2001). Garland Science.
Free to read on NCBI Bookshelf.
TextbookEducational